Ohio State University Study: COVID-Vaccinated Patients Die at Near Double the Rate than Non-Vaccinated, Hospitalized COVID-19 Patients

All of the health authorities have repeatedly conveyed that the COVID-19 vaccines would keep morbidity and mortality rates down and there is plenty of evidence in the form of hundreds of observational studies reviewed by TrialSite to support that claim. Although the durability of the vaccines is such that boosters are necessary for the at-risk at least annually. However, what has not been studied is what happens to hospitalized COVID-19 patients: are the COVID-19 vaccinated better off than the unvaccinated once both are hospitalized? To find out, a group of scientists and physicians from multiple Ohio State University departments and institutes including the academic medical center&rsquo;s medical facility conducted a single-center study involving 152 adult patients admitted to Ohio State University hospital with acute respiratory failure from May 20, 2020, through November 2022, including 112 patients positive with COVID-19 and 40 patients that were deemed negative for COVID-19. Out of the COVID-19 vaccinated cohort, 23 were vaccinated for SARS-CoV-2, and 89 were not vaccinated. Of the non-vaccinated patients infected with COVID-19, 46 were admitted before and 43 after COVID-19 vaccines were approved. During the study throughout the over two-year duration investigators measured and analyzed the hospitalized COVID-19 patients for SARS-CoV-2 Ab levels corresponding to a suite of demographic attributes and clinical parameters. Also, the study team monitored IgG4 Ab concentrations comparing this measurement in both vaccinated and unvaccinated cohorts of the study. What resulted is frankly, shocking. Hospitalized patients vaccinated against COVID-19 die at nearly double the rate of non-vaccinated patients. The results raise significant questions that must be addressed, yet this study&rsquo;s outcomes were covered by little to no media. 
This is an important study given the mixed data on the influence of COVID-19 vaccination once patients are hospitalized, the study was supported by the National Institutes of Health (NIH).